Why is leukocyte reduction needed?

RZ-200
Performance Summary
Facility A
Blood Age
(day(s))		 Volume
(mL)		 Pre-filtration
WBCx108		 Post-filtration
WBCx105
1 266 27.66 0.47
1 316 29.39 1.14
1 303 22.73 0.55
1 304 23.41 1.10
1 275 27.50 0.49
1 317 36.77 1.72
1 284 22.44 0.51
1 297 20.79 1.60
1 306 59.36 2.19
2 292 17.81 0.53
2 314 23.24 1.14
2 296 38.18 1.06
2 335 26.13 0.61
2 287 24.11 1.03
3 295 42.78 0.53
3 312 13.10 1.13
3 327 22.89 0.59
3 296 23.38 0.53
Blood :Red cells, Additive solution(SAG-M)
Post-WBC was determined by Nageotte chamber method
Evaluation facility : CRTS in France
Facility B
Blood Age
(day(s))		 Volume
(mL)		 Pre-filtration
WBCx108		 Post-filtration
WBCx105
3 265 1.70 0.05
3 246 0.79 < 0.04
3 237 4.04 0.34
3 214 7.96 < 0.04
3 267 4.52 < 0.05
3 269 1.18 0.05
3 264 1.45 0.05
3 251 2.77 0.18
3 221 0.55 0.08
3 274 1.92 < 0.05
3 282 9.60 0.21
Blood :Red cells, Additive solution(SAG-M), Buffy coat removed
Post-WBC was determined by Nageotte chamber method
Evaluation facility : CRTS in France
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RZ-500
Performance Summary (in vitro)
Facility A
Blood Age
(day(s))		 Volume
(mL)		 Pre-filtration
WBCx108		 Post-filtration
WBCx105
1 525 11.01 1.19
1 355 96.79 2.42
2 347 69.26 3.30
23 442 1.25 0.99
23 427 4.75 0.97
23 459 1.43 1.02
23 465 0.88 1.04
23 354 1.07 0.84
27 226 0.70 0.57
27 344 0.98 0.83
27 602 1.17 1.34
28 398 2.03 0.90
29 439 1.72 0.97
30 434 7.13 0.92
31 455 3.04 1.01
33 431 2.61 0.93
Blood :Red cells, in additive solution (SAG-M), buffy coat removed
Post-filtration WBC number was determined by Nageotte chamber method
Evaluation facility : Zentrum für Blut-und Krebserkrankungen
Institut für Transfusionsmedizin, Berlin Germany
Facility B
Blood Age
(day(s))		 Volume
(mL)		 Pre-filtration
WBCx108		 Post-filtration
WBCx105
19 423 6.35 0.85
19 427 8.84 0.85
19 400 9.61 1.29
20 420 5.17 0.84
20 416 5.21 0.83
20 431 5.24 0.86
20 320 4.25 0.97
20 441 6.32 0.88
20 414 6.40 0.83
20 409 7.72 0.82
21 401 6.30 1.25
21 419 5.78 0.84
21 421 5.35 1.31
22 415 7.87 0.83
Blood :Red cells, in additive solution(SAG-M), buffy coat removed
Post-filtration WBC number was determined by Nageotte chamber method
Evaluation facility : National Blood Service, Manchester Blood Center, Manchester UK
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Sepacell filter units are manufactured by Asahi Kasei Medical Co., Ltd.
Sepacell filter products, filter units with tubing kits, are produced by Asahi Kasei Kuraray Medical Co., Ltd.
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