About the Enzymes Business

Ever since the early 1970s when we succeeded in industrializing enzymes for lipid analysis, we have supplied more than one hundred enzymes for diagnostic products.
We have also been working closely together with our customers from the initial stages of development, and have introduced new measurement methods to the world. We also offer many products that are compliant with REACH.

Strengths in research and technological development

Development of new and unique enzymes

We have our uniquely owned microorganism library and genome database that we can scan through to enable us to swiftly develop and propose new and unique enzymes that meet your needs. We also have a uniquely developed host microbial group, which allows us to manufacture even difficult-to-express enzymes at a practical level.

Speedy development of the production process

We draw out the enzyme production capability of the host microorganism to its maximum level by making use of culture development techniques that have been optimized for each host microbial group. In addition, our technological capabilities in building flexible purification processes tailored to the characteristics of the enzymes enable their rapid mass production.

Large-scale manufacturing technologies

We make use of our many years of experience in enzyme production and have a strict quality management structure to achieve stable production of high-quality enzymes.

Research results

Disruption of SMC-related genes promotes recombinant cholesterol esterase production in Burkholderia stabilis.

Applied Microbiology and Biotechnology vol. 106,24 (2022): 8093-8110.
Konishi, Kenji et al. DOI: 10.1007/s00253-022-12277-3

Novel enzymatic method for assaying Lp-PLA2 in serum.

Clinica Chimica Acta; International Journal of Clinical Chemistry vol. 481 (2018): 184-188.
Yamaura, Saki et al. DOI: 10.1016/j.cca.2018.03.012

Characterization and application of a novel nicotinamide mononucleotide adenylyltransferase from Thermus thermophilus HB8.

Journal of Bioscience and Bioengineering vol. 125,4 (2018): 385-389.
Konishi, Kenji et al. DOI: 10.1016/j.jbiosc.2017.10.017

Areas of adoption

Diagnostic products manufacturers

Biosensor manufacturers

Manufacturers of raw materials for pharmaceutical additives


We have acquired ISO 9001 certification.

Distributor information

Note: If you are in Japan or in areas not listed below, please contact us via the inquiry form.

East Asia


Sales areas:China

DARGON YEA Material Technology CO., LTD.

Sales areas:Taiwan

SAMOH Pharm/SAMOH Farmachem

Sales areas:South Korea


Sales areasSouth Korea


Sekisui Diagnostics (UK) Limited

Sales areas:Albania/Andorra/Austria/Belarus/Belgium/Bosnia/Bulgaria/Croatia/Cyprus/Czech Republic/Denmark/Estonia/Finland/France/Germany/Greece/Hungary/Iceland/Ireland/Italy/Latvia/Liechtenstein/Lithuania/Luxembourg/Macedonia/Malta/Moldova/Monaco/Netherlands/Norway/Poland/Portugal/Romania/Russia/San Marino/Slovakia/Slovenia/Spain/Sweden/Switzerland/Turkey/Ukraine/United Kingdom/Vatican City/Yugoslavia

North America, Central America, South America

Sekisui Diagnostics (UK) Limited

Sales areas:Argentina/Bolivia/Brazil/Canada/Chile/Colombia/Costa Rica/Cuba/Ecuador/El Salvador/French Guiana/Guatemala/Guyana/Honduras/Mexico/Nicaragua/Panama/Paraguay/Peru/Suriname/United States/Uruguay/Venezuela/West Indies


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