Summary of the Test Item

• High serum Lp-PLA2 activity is a risk factor for coronary artery disease.
• Guidelines*1 recommend the Lp-PLA2 test to predict the risk of future onset of cardiovascular diseases.
• Particularly in the United States and China, the market for Lp-PLA2 tests is growing.

*1 

2014 – International Atherosclerosis Society

2016 – American Heart Association/American Stroke Association

2017 – American Association of Clinical Endocrinologists and American College of Endocrinology



Asahi Kasei Solutions

Reagent for Enzymatic Assay of Lp-PLA2 Materials and Methods

The Lp-PLA2 Activity Assay Reagent (Enzymatic Assay)*2, *3 by Asahi Kasei is characterized by its versatility, which makes it highly convenient, and its endogenous substrate.

*2 Novel enzymatic method for assaying Lp-PLA2 in serum. Clinica Chimica Acta; International Journal of Clinical Chemistry vol. 481 (2018): 184-188. Yamaura, Saki et al. DOI: 10.1016/j.cca.2018.03.012
*3 Patented in Japan, the United States, and China

Versatility

Asahi Kasei
Enzymatic method

Chemical method

ELISA

Number of reagents

2

2–3

Many

Calibration points

2

2–5

Many

Compatibility with general purpose automated biochemical analyzers

Yes

Partially

No

Reagent stability

≥12 months

NA

NA

The reagent for the enzymatic assay by Asahi Kasei is stable for 12 months or longer under refrigeration.
We simplify reagent development by supplying the components, materials, and production procedures.

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Measurement Principle
Correlations with Each Assay Method

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