Asahi Kasei Medical
  • Site Map
  • Contact Us
  • Font size: Small
  • Font size: Medium
  • Font size: Large
  • Home
  • Our Approach to Business
  • Corporate Information
  • News
  • Products
  • Patients and Families

Diseases

L

Lambert-Eaton myasthenic syndrome (LEMS)

Lambert-Eaton myasthenic syndrome (LEMS) is a disease of the neuromuscular junction characterized by muscle weakness, tingling sensations in affected sites, fatigue, and dry mouth. LEMS is thought to be caused by the production of antibodies targeting antigens in the neuromuscular junction. Corticosteroids, plasmapheresis, and IVIg are used for treatment.

Applied therapies

Applied products

Top of Page

M

Miller-Fisher syndrome (MFS)

Miller-Fisher syndrome (MFS) is a rare, acquired nerve disorder, considered to be a variant of Guillain-Barré syndrome. The etiology remains unknown but in most cases it occurs after a viral infection. IVIg and plasmapheresis are used for the treatment of MFS.

Applied therapies

Applied products

Multiple myeloma/ Primary macroglobulinemia

Antibodies (immunoglobulins; IgG, IgA, IgM, IgD, IgE) are produced by plasma cells in the bone marrow and play a role in the immune response. The principal cause of multiple myeloma and primary macroglobulinemia is the excessive multiplication of plasma cells by canceration. Abnormal immunoglobulin called IgM or M protein is produced, and the detection of this marker is the key to the diagnosis.
Symptoms of multiple myeloma are lower back pain, back pain, bone pain, lassitude, fatigue, anemia, susceptibility to infection, proneness to fracture, protein in the urine, and elevated erythrocyte sedimentation rate. Common symptoms of primary macroglobulinemia are enlarged lymph nodes, liver, and spleen.
Elevated serum M protein levels increase blood viscosity, leading to circulatory disorders. The resulting deterioration in kidney function is another common symptom of multiple myeloma and primary macroglobulinemia. In addition to medical treatment, double filtration plasmapheresis (DFPP) or plasma exchange (PE) is used to reduce M protein levels to reduce viscosity and improve blood circulation.

Applied therapies

Applied products

References

Multiple sclerosis (MS)

Multiple sclerosis (MS) is an unpredictable disease of the central nervous system characterized by visual disorders and muscle weakness. MS is thought to be an autoimmune disorder mainly of the Th1-type cellular immune response targeting oligodendrocytes. Treatment includes corticosteroid pulse therapy, corticosteroids in combination with immunosuppressants, and plasmapheresis combined with immunosuppressants.

Applied therapies

Applied products

References

Myasthenia gravis(MG)

Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease characterized by varying degrees of skeletal muscle weakness. MG is thought to result from inhibition of neuromuscular transmission by autoantibodies targeting the acetycholine (ACh) receptors on the postsynaptic membrane in the myoneural junction. Treatment for MG includes thymectomy, plasmapheresis, and high-dose intravenous immunoglobulin (IVIg).

Applied products

References

Top of Page

Contact Us

Please feel free to send us any questions you may have about our products and support.

Contact Us

Your Voice

Share your feelings and experiences when using our products.

Your Voice
Note: It might be required in your country that medical devices shall be officially registered and/or approved by an authorized organization. Please contact our representative in your region or contact us to confirm whether the listed products are approved for use. These information may contain general information on medical-related topics and is not meant to provide specialist advice or instructions concerning the products and services sold by Asahi Kasei Medical. Please contact us directly for special inquiries. You should not use this information for diagnosing a health problem or disease but should always consult your own physician.Contact us

Top of page