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Plasmapheresis

Overview

What is therapeutic plasmapheresis?

Therapeutic plasmapheresis is an extracorporeal blood purification technique designed for the removal of pathogenic substances from the plasma of patients. Examples of these substances include pathogenic autoantibodies, immune complexes, cryoglobulins and cholesterol-containing lipoproteins.

Possibilities of Plasma Apheresis

Removal of antibodies

  • Alloantibodies
  • Autoantibodies
  • Immune Complexes

Removal of excessive or abnormal substances

  • Paraproteins
  • Cholesterol in Hypercholesterolaemia

Removal of toxins

  • Protein-bound Drugs / Toxins
  • Mushroom Poisons

Modalities of therapeutic plasmapheresis

Therapeutic plasmapheresis includes the following three modalities.

  • Plasma Exchange (PE)
  • Double Filtration Plasmapheresis (DFPP)
  • Immunoadsorption (IA) / Plasma Adsorption (PA)

Mechanism of membrane plasma separation

Plasma and proteins pass through the membrane but the pores are small and cellular components cannot pass across the membrane.

Plasma and pathogenic substances in the plasma can be discarded or purified and returned to the patient.

Applied diseases of plasmapheresis

Please see below for conditions for which Plasmapheresis is indicated.

Applied diseases

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Note: It might be required in your country that medical devices shall be officially registered and/or approved by an authorized organization. Please contact our representative in your region or contact us to confirm whether the listed products are approved for use. These information may contain general information on medical-related topics and is not meant to provide specialist advice or instructions concerning the products and services sold by Asahi Kasei Medical. Please contact us directly for special inquiries. You should not use this information for diagnosing a health problem or disease but should always consult your own physician.Contact us

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